Clinical features (choose any six below) of giant cell arteritis include:
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Temporal headache due to temporal artery ischaemia
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Decreased vision due to either arteritic ischaemic optic neuropathy (most
common), retinal artery , vein occlusion or choroidal ischaemia (less common)
-
Jaw claudication
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Tongue claudication
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Weight loss or anorexia
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Malaise, fatigue or weakness
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Fever
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Polymyalgia rheumatica
or
Pathological features:
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Raised ESR
-
Raised CRP
Abnormal histological features of the temporal artery which include:
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fragmentation of the internal elastic lamina
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granulomatous inflammation of the vessel wall
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nodular necrosis of the media
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full-thickness scarring of the vessel wall in “burnt out” cases
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