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In this section, important trials from the past 20 years are summarized in an easily digestible form. Many of the trials have influenced the ways ophthalmology is practised nowadays. References are given at the end of each trials for further consultation. 
NOTE: Because of the rapid development in ophthalmology, some of the results from these trials should be re-interpreted in the light of newer medical management. For example, the early glaucoma trials did not use prostaglandin analogues such as latanoprost which is now widely used to lower the intraocular pressure effectively.
Some of the studies have been included in the electronic book "Studies you need to know for final MRCOphth/ MRCS/ FRCS" under the section of e-books in this site. Any comments or contributions please e-mail to: chuaoxford@hotmail.com
GLAUCOMA TRIALS
Ocular Hypertension Treatment Study
(OHTS)

Early Manifest Glaucoma Trial
(EMGT)

Advanced Glaucoma Intervention Study
(AGIS)

Glaucoma Laser Trial Followup Study
(GLTFS)

Collaborative Initial Glaucoma Treatment Study
(CIGTS)

Fluorouracil Filtering Surgery Study
(FFSS)

CORNEA TRIALS
Herpetic Eye Disease Study (HEDS) I

Herpetic Eye Disease Study (HEDS) II

ENDOPHTHALMITIS TRIALS
Endophthalmitis Vitrectomy Study (EVS)

OPTIC NEURITIS TRIALS
Optic Neuritis Treatment Trial (ONTT)

ARMD  TRIALS
Age-Related Eye Disease Study (AREDS)

Macular Photocoagulation Study (MPS)

Treatment of AMD with Photodynamic Therapy (TAP)

DIABETES TRIALS
Diabetic Retinopathy Study (DRS)

Early Treatment Diabetic Retinopathy
Study (ETDRS)

Diabetic Retinopathy Vitrectomy Study (DRVS)

Diabetes Control and Complications Trial (DCCT)

United Kingdom Prospective Diabetes Study (UKPDS)

VEIN OCCLUSION TRIALS
Branch Vein Occlusion Study 
(BVOS)

Central Vein Occlusion Study
(CVOS)

VARIOUS RETINA STUDIES
The Silicone Study

ANTI-VEGF STUDIES
Macugen

MARINA

ANCHOR
Central Retinal Vein Oxx

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