What does the above specimen show? Answer A mushroom-shaped choroidal lesion with overlying retinal detachment. This appearance is typical of choroidal melanoma. What factors will affect this patient's prognosis? a Answer Size of the lesion (large lesion poor prognosis) Location of the lesion (anteriorly placed lesion poorer prognosis as diagnosis tends to be later) Cell type (epithelioid cell type has the worst prognosis) Extraocular invasion or metastasis Is this the most common neoplasm of the choroid? If not, what is ? a Answer No. Metastatic carcinoma is the most common neoplasm in the choroid. Lung cancer and breast cancer are the two commonest sources of metastasis in male and female respectively.