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Corkwood elm
(Duboisia
myoporoides) is a shrub native
to Australia and New Caledonia. It contains an alkaloid
duboisine in its leaves which has similar chemical
composition as hyoscyamine. J. Bancroft of Brisbane was
the first to experiment and use it clinically. Like atropine,
topical application causes mydriasis and cycloplegia.
Unlike atropine, its effects are shorter and less irritating
to
the eye. |
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