What is Vogt-Koyanagi-Harada's syndrome?

Answer
It is a multi-systemic disorder of unknown aetiology affecting people
between the age of 30 and 50. The ocular features include bilateral panuveitis, neurological and dermatological signs.
 

How common is Vogt-Koyanagi-Harada's syndrome in UK?

Answer
Rare. The condition occurs mainly in Japanese and people from the far East.
 

How can VKH syndrome be further classified?

Answer
VKH can be classified into Vogt-Koyanagi syndrome and Harada syndrome.
Vogt-Koyanagi syndrome is characterized by bilateral anterior granulomatous uveitis and dermatological features including vitiligo, poliosis and alopecia.
Harada's syndrome is characterized by bilateral posterior uveitis and neurological features. The neurological features include:
central nervous system lesion with meningeal irritation, encephalopathy
and CSF lymphocytosis
auditory signs of tinnitus and deafness.
 

What are the features of acute posterior uveitis in this condition?

Answer
Severe bilateral uveitis with severe vitritis. Detachment of the retina and optic swelling are common.
 
 

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